Articles
Diseases of haem dysfunction and study of the basis of Rett syndrome
9.9.2007 | Articles - biotech and pharmacy
Study of the molecular basis of the haem metabolism disorders, impact of the lowered availability of haem synthesis on mitochondria biogenesis, haem metabolon in connection with changes of haem availability (haemoproteins)
Phylogenetic Analysis of Haloalkane Dehalogenases
6.9.2007 | Articles - biotech and pharmacy
Haloalkane dehalogenases (HLDs) are enzymes that catalyze the cleavage of carbon halogen bonds by a hydrolytic mechanism. Although comparative biochemical analyses have been published, no classification system has been proposed for HLDs, to date, that reconciles their phylogenetic and functional relationships. In the study presented here we have...
Identification of Tunnels in Proteins, Nucleic Acids, Inorganic Materials and Molecular Ensembles
30.8.2007 | Articles - biotech and pharmacy
The knowledge of the access paths connecting interior of molecular systems with surrounding environment is important for understanding of structure-function relationships and engineering of molecules for biotechnological applications. CAVER is a computer program developed for calculations of tunnels, channels or pores in the biomolecules,...
Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
23.8.2007 | Articles - biotech and pharmacy
Wnt/beta-catenin signaling regulates many processes during vertebrate development. To study transcriptional targets of canonical Wnt signaling, we used the conditional Cre/loxP system in mouse to ectopically activate beta-catenin during central nervous system development.
Lambda's new mini syringe pump
20.8.2007 | Articles - biotech and pharmacy
Lambda presents a new subminiature syringe pump “DOZITO”, which is many times smaller than any other laboratory pump on the market. It uses a completely new motion principle (no motors, no electromagnets, no compressed gas and the like).
Fruit – fuel of future?
14.8.2007 | Articles - biotech and pharmacy
A lot of researchers are nowadays focused on biofuels. Biofuels which are now used are called first generation of biofuels. These fuels suffer from several disadvantages. It is reason why research of new biofules is needed. One of biofuel of second generation could be 2,5-dimethylfuran (DMF) a liquid transportation fuel with 40% greater energy...
European Research Programme for the Partitioning of Minor Actinides from Highly Active Wastes Issuing the Reprocessing of the Spent Nuclear Fuel
10.8.2007 | Articles - biotech and pharmacy
The consortium of IP EUROPART consists of 25 academic and industrial research institutions from 10 European countries, inclusive four partners from the Czech Republic. The research and development concerns the partitioning of long-lived radionuclides (LLRN), which are present in the nuclear waste, and aspects in conjunction with reprocessing of...
Structure-functional studies on lectins from pathogenic organisms and their interactions with carbohydrates
3.8.2007 | Articles - biotech and pharmacy
Carbohydrates are an essential component of life as a structural and energy storage component, and as stabilization, recognition, signaling and communication agents. The multiple roles of carbohydrates arise from the stability and the stereochemical diversity of glycosidic bonds. The unique branching structure of carbohydrates has inherent...
POLYHYDROXYALKANOATES – THE BIODEGRADABLE PLASTICS
27.7.2007 | Articles - biotech and pharmacy
In the second half of the twentieth century, a production of certain materials truly skyrocketed, a group of materials never seen before on our planet. They were synthetic polymers, also known as plastics. These materials are very heterogenous considering both properties and practical use, but there is one common property to all of them – a high...
Unique Czech biotechnologies can make billion-worth business in Russia
27.7.2007 | Topic of the month
The Russian cosmic industry seeks new ways of exploiting its free capacities, and one of its biggest projects includes a major role of a unique Czech patented biotechnology. The technology solves the waste water disposal and purification including further utilization of the sludge for production of energy or high-quality fertilizers. The total...
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