Czech Biotechnology News

Touch-down reverse transcriptase-PCR detection of IgV(H) rearrangement and Sybr-Green-based real-time RT-PCR quantitation of minimal residual disease in patients with chronic lymphocytic leukemia.

17.3.2006   |   Czech Biotechnology News

Institute of Hematology and Blood Transfusion, Prague, Czech RepublicInstitute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic. pekova@img.cas.cz

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Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.

17.3.2006   |   Czech Biotechnology News

[Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic.] Quaternary benzo[c]phenanthridine alkaloids (QBA) sanguinarine and chelerythrine exhibit a wide spectrum of biological activities whence they are used in dental care products. Recent studies indicated that...

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Intensity-modulated radiotherapy in the treatment of thyroid cancer

16.3.2006   |   Czech Biotechnology News

[Univerzita Karlova v Praze, Lekarska fakulta v Hradci Kralove, Klinika onkologie a radioterapie. vosmik@fnhk.cz] The main problem of the conventional radiotherapy in postoperative or curative irradiation in thyroid cancer is to achieve a sufficient dose in the planning target volume with acceptable dose distribution homogeneity and at the same...

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The FUT1 and ESR genes--their variability and associations with reproduction in Prestice Black-Pied sows.

16.3.2006   |   Czech Biotechnology News

[Department of Genetics, Mendel University of Agriculture and Forestry Brno, Czech Republic. xhorak02@node.mendelu.cz] The determination of genetic variability by means of molecular genetic markers FUT1 and ESR2, and the evaluation of their associations with reproduction traits in population of Prestice Black-Pied sows have been...

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Thermoluminescence and fluorescence study of changes in Photosystem II photochemistry in desiccating barley leaves.

16.3.2006   |   Czech Biotechnology News

[Department of Experimental Physics, Faculty of Sciences, Palacky University, tr. Svobody 26, 771 46, Olomouc, Czech Republic] An effect of desiccation (a decrease of relative water content from 97% to 10% within 35 h) on Photosystem II was studied in barley leaf segments (Hordeum vulgare L. cv. Akcent) using chlorophyll a fluorescence and...

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Differential effects of selected natural compounds with anti-inflammatory activity on the glucocorticoid receptor and NF-kappaB in HeLa cells.

15.3.2006   |   Czech Biotechnology News

[Institute of Medical Chemistry and Biochemistry, Medical Faculty, Palacky University Olomouc, Hnevotinska 3, 77515 Olomouc, Czech Republic]

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Functional polymer hydrogels for embryonic stem cell support.

14.3.2006   |   Czech Biotechnology News

[Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, CZ-140 00 Praha 4, Czech Republic.] Embryonic stem (ES) cells are pluripotent cells with the ability to differentiate among all embryonic and adult cell lineages. Derivation of human ES cells opened up the way for treatment of many serious disorders...

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The molecular screening of the stool for the colorectal carcinoma

13.3.2006   |   Czech Biotechnology News

[Chirurgicka klinika, 3. LF UK a FNKV Praha. rene.voboril@seznam.cz] BACKGROUND: Current screening methods of colorectal carcinoma are based on examination of occult bleeding in the stool, and further on endoscopic and irrigographical (barium enema) examinations. Population-based non-invasive screening method having high sensitivity and...

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Transcription factor c-Myb is involved in the regulation of the epithelial-mesenchymal transition in the avian neural crest.

13.3.2006   |   Czech Biotechnology News

[Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 166 37 Prague, Czech Republic] Multipotential neural crest cells (NCCs) originate by an epithelial-mesenchymal transition (EMT) during vertebrate embryogenesis.

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Role of microtubules network in CYP genes expression.

13.3.2006   |   Czech Biotechnology News

[Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University Olomouc, Hnevotinska 3, 77515 Olomouc, Czech Republic.] Superfamily of cytochrome P450 enzymes (CYPs), a distinctive enzyme system by which human body defends itself against toxic compounds, is the subject of a complex regulation process involving various...

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