Czech Biotechnology News
Basic fibroblast growth factor and its receptors in human embryonic stem cells.
13.3.2006 | Czech Biotechnology News
[Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.] Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to self-renew and differentiate into various cell types of endodermal, ectodermal or mesodermal origin.
Identification of potential human oncogenes by mapping the common viral integration sites in avian nephroblastoma
13.3.2006 | Czech Biotechnology News
[Institute of Molecular Genetics AS CR, Prague, Czech Republic.] Gene deregulation is a frequent cause of malignant transformation. Alteration of the gene structure and/or expression leading to cellular transformation and tumor growth can be experimentally achieved by insertion of the retroviral genome into the host DNA.
Gene Therapy Progress and Prospects – Vectorology: design and production of expression cassettes in AAV vectors
2.3.2006 | Czech Biotechnology News
Adeno-associated virus (AAV) derived vectors are considered highly eligible vehicles for human gene therapy.
Generation of a functional mammary gland from a single stem cell
2.3.2006 | Czech Biotechnology News
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2.3.2006 | Czech Biotechnology News
The development of an oncogenic state is a complex process involving the accumulation of multiple independent mutations that lead to deregulation of cell signalling pathways central to the control of cell growth and cell fate1, 2, 3.
Biotech Food Myths, Misconceptions and Misinformation - A Response to False Activist Claims
2.3.2006 | Czech Biotechnology News
On June 15, a group of anti-biotech organic food activists calling themselves the "Independent Science Panel" issued a report called The Case for a GM-Free Sustainable World, regarding crops and foods improved using modern biotechnology techniques. That report makes a series of claims regarding bioengineered crops that is not supported by the...
Distribution and function of plasmids in Salmonella enterica
1.3.2006 | Czech Biotechnology News
Plasmids of Salmonella enterica vary in size from 2 to more than 200 kb. The best described group of plasmids are the virulence plasmids (50-100 kb in size) present in serovars Enteritidis, Typhimurium, Dublin, Cholerae-suis, Gallinarum, Pullorum and Abortus-ovis.
Detection of Lawsonia intracellularis in wild boar and fallow deer bred in one game enclosure in the Czech Republic
1.3.2006 | Czech Biotechnology News
The prevalence of Lawsonia intracellularis between wild boar (Sus scrofa) and fallow deer (Dama dama) bred in one game reserve was investigated using the nested PCR method. In the study, 88 clinically healthy wild boars of different age categories and two fallow deer bagged in the game reserve were examined.
Possible genetic damage in the Czech nuclear power plant workers
1.3.2006 | Czech Biotechnology News
The aim of our study was to identify occupational risk of irradiation exposure in the Czech nuclear power plant workers. We analyzed levels of chromosomal aberrations, a well-known biomarker of early biological effects and a predictor of cancer risk.
Polyhydroxyalkanoates for tissue engineering
16.1.2006 | Czech Biotechnology News
Polyhydroxyalkanoates (PHA), polyesters produced by microorganisms under unbalanced growth conditions (Doi 2002) have potential applications for medical and pharmaceutical purposes. The primary factor is because of their biodegradability. Nevertheless other favorable qualities such as their adaptability to suit the requirements of different...
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