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Electrically activated glue patch repairs blood vessels from within

Date: 3.5.2021 

Back in 2015, we heard about an electrically activated glue that could be used to bond items in wet conditions, or even underwater. Now, scientists have demonstrated that the material could be used to patch leaky blood vessels … from the inside.

Kredit: Nanyang Technological University.Named Voltaglue, the adhesive was first created by a team at Singapore's Nanyang Technological University, and has since been developed in partnership with MIT.

It takes the form of a hydrogel, which contains carbon molecules known as carbenes that are grafted onto tree-branch-shaped polymeric molecules called dendrimers. When the gel is subjected to an electrical charge, the carbenes are drawn towards any nearby surfaces. The dendrimers, which get dragged along with the carbenes, hook onto those surfaces, forming a bond. The higher the charge, the stronger the bond becomes.

In recent experiments, a small Voltaglue-coated patch was applied to the end of a flexible balloon catheter, which was then inserted into a pig aorta. Although the blood vessel had been removed from the animal, it was hooked up to a mock heart and was subjected to continuous blood flow at a rate of 10 ml per minute.

The technology has been patented, and is now being commercialized as the ePATCH electrically activated patch and the CATRE wired catheter. Along with its use in blood vessels, it could also be utilized in body parts such as the intestines and oesophagus.





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