Scientists Discover Key Step for Regulating Embryonic Development

Deleting a gene in mouse embryos caused cardiac defects and early death, leading researchers to identify a mechanism that turns developmental genes off and on as an embryo matures, a team led by a scientist at The University of Texas.

“Our findings provide a new window through which to look at epigenetic control,” Yeh said, “and how epigenetics and development are unexpectedly tied together by the SUMO/SENP2 system.” Said senior author Edward T.H. Yeh.

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