Datum: 16.8.2008
The problem with using a shotgun to kill a housefly is that even if you get the pest, you'll likely do a lot of damage to your home in the process. Hence the value of the more surgical flyswatter.
Cancer researchers have long faced a similar situation in chemotherapy: how to get the most medication into the cells of a tumor without "spillover" of the medication adversely affecting the healthy cells in a patient's body.
Whole article on sciencedaily
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