Date: 11.4.2007
Short chromosomes put cancer cells in forced rest - A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres "Normally, when telomeres get critically short, the cell commits suicide as a means of protecting the body," says Carol Greider, Ph In an unusual set of experiments, the research team first mated mice with nonoperating telomerase to mice carrying a mutation that predisposed them to Burkitt’s lymphoma, a rare but aggressive cancer of white blood cells Whole article: http://www (27.4.2007)
Cheap molecule may attack tumors - A cheaply-produced molecule may be the key to treating a variety of cancers, claim Canadian researchers Dicholoroacetate (DCA) has been suggested for years as a possible treatment for certain rare metabolic disorders in children The University of Alberta team, writing in the journal Cancer Cell, now say it could encourage cancer cells to die Experts say much more research will be needed before an effective cancer treatment can emerge Whole article onnews (23.4.2007)
New Cell Type Identified In Cancer Development - Scientists have discovered a new type of cell that appears to play a role in the development of cancer -- a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues Current cancer stem cell theory holds that tumors are comprised of a variety of cell types Cancer stem cells were first identified in leukemia, but they have also been found in breast, brain, colon and prostate cancers But a team of scientists, led by Dr Whole article: www (21.3.2007)
Scientists look at precancerous cells - Researchers in Boston have identified how a missing protein causes tissue to become precancerous, the Massachusetts Institute of Technology announced The finding could help identify patients at risk of developing tumors, MIT said Most breast and prostate tumors are missing the protein but it has not been clear what role the protein, known as 14-3-3 sigma, played in tumor growth "The cells try to divide and try to divide, and they just give up Whole article: www (19.3.2007)
Researchers Identify Ovarian Cancer Biomarkers - Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors The team of researchers from the University of Michigan, University of Pennsylvania, and universities in Greece and Italy, used a laser technique to isolate blood vessel cells from 21 ovarian tumors and four normal ovarian tissue samples The results identified more than 70 markers that were present in large amounts in the blood vessels of cancer tissue but not in the vessels of normal tissues "Some of these genes, depending on how highly expressed they were in the tumor vasculature, were also prognostic of a patient's survival Whole article: www (12.3.2007)
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