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Genes Associated With Adverse Reactions To Cancer Radiotherapy Treatment Identified

Date: 21.4.2007 

Medical scientists at the University of Leicester have announced a potentially unique advance in breast cancer research by identifying two genes associated with adverse reaction to cancer treatment. The research could mean people who might react badly to radiotherapy could be warned in advance or alternative treatments be sought. There is no test at present for an abnormal reaction to radiotherapy. No-one in the past has proposed such a test. The team who carried out the study included Drs Paul Symonds, Mark Plumb, Irene Peat and George Giotopoulos of the Department of Cancer Studies and Molecular Medicine and the Department of Genetics at the University of Leicester. Their results are published in the British Journal of Cancer.... Whole article on "ScienceDaily":[ www.sciencedaily.com]

Cheap molecule may attack tumors - A cheaply-produced molecule may be the key to treating a variety of cancers, claim Canadian researchers Dicholoroacetate (DCA) has been suggested for years as a possible treatment for certain rare metabolic disorders in children The University of Alberta team, writing in the journal Cancer Cell, now say it could encourage cancer cells to die Experts say much more research will be needed before an effective cancer treatment can emerge Whole article onnews (23.4.2007)

Scientists Stop Genes that Help Breast Cancer to Spread - US scientists have demonstrated a way to stop breast cancer spreading to other parts of the body by either switching off the genes involved or blocking them with drugs Tumours formed from cancer that has spread or metastased from the primary site to other parts of the body cause 90 per cent of cancer deaths The process of metastasis or cancer spread is still much of a mystery to scientists Dr Joan Massagué from the Memorial Sloan-Kettering Cancer Center in New York, US, has been working in this field for some time Whole article www (13.4.2007)

Simulated Populations Used To Probe Gene Mapping - More powerful computers are allowing scientists and engineers to conduct simulations that grow more realistic each year In a new study published in the journal PLoS Genetics, statisticians and genetic epidemiologists from Rice University and The University of Texas M "In a real population, you never have the complete genetic picture, particularly for complex diseases where more than one gene is implicated and where environmental factors play a role," said lead author Bo Peng of M Whole article: www (27.3.2007)

New findings on the genomic guardian - p53 protein - The p53 protein routinely shuts down damaged cells and is one of our main lines of defence against cancer The p53 transcription factor is found in every cell of the body, where it helps to prevent cancer by activating and deactivating the right genes Almost half of all cancer tumours involve a mutation of the gene for p53, and in the hope of developing new cancer therapies, many cancer researchers study the mechanisms the protein controls read more www (22.3.2007)

New Cell Type Identified In Cancer Development - Scientists have discovered a new type of cell that appears to play a role in the development of cancer -- a highly volatile, precancerous stem cell that can either remain benign or become malignant, depending upon environmental cues Current cancer stem cell theory holds that tumors are comprised of a variety of cell types Cancer stem cells were first identified in leukemia, but they have also been found in breast, brain, colon and prostate cancers But a team of scientists, led by Dr Whole article: www (21.3.2007)

 

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