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Visit Mendel Lectures this Thursday!

Date: 17.4.2012 

Professor Dr. Roland Kanaar studied chemistry at Leiden University and obtained his Ph.D. degree in 1988 for research on the action of an enhancer in site-specific DNA recombination and the elucidation of how nucleoprotein complexes assembled at distant sites along a DNA chain communicate with each other to provide selectivity during recombination. His post-doctoral work at the University of California, Berkeley aimed at understanding mechanisms of homologous recombination (with Nick Cozzarelli) and at understanding how proteins and RNA interact to achieve accurate but flexible recognition of splice sites (with Don Rio).

His current research addresses the mechanisms and biological relevance of genome surveillance processes with particular emphasis on homologous DNA recombination and DNA double-strand break repair. Genome surveillance is essential to prevent chromosomal abnormalities, which in their turn may lead to hereditary diseases, cancer or cell decay. In 2000 he was appointed Professor of Molecular Radiation Genetics. Prof. Kanaar is a scientific co-founder of the biotechnology company DNage, which is focused on the development of products for medical and health problems associated with ageing. In 2002 he was elected as a member of the European Molecular Biology Organization.




Photohttp://www.mendellectures.muni.cz/2011-2012/how-dna-recombination-maintains-genome-integrity, www.sxc.hu

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