Date: 14.12.2010
New research identifies two genetic variants that increase the risk of developing endometriosis, a common gynaecological disease. The study provides clues to the origin of this often very painful condition, which has a significant impact on the quality of life of sufferers.
Researchers have identified two new genetic variants that increase the risk of developing the disease, particularly moderate-severe stages.
The first is a variant on chromosome 7 believed to be involved in regulating nearby genes, probably those involved in the development of the womb and its lining. The second variant was found on chromosome 1, close to the gene WNT4. This is important for hormone metabolism and the development of the female reproductive tract, especially the ovaries, making it an important biological candidate for involvement in endometriosis.
Source:
http://www.wellcome.ac.uk/News/Media-office/Press-releases/2010/WTX063800.htm
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