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CRISPR-Cas10 can flood virally infected bacteria with toxic molecules, researchers discover
Credit: Andrii Muzyka.Fotolia.com

CRISPR-Cas10 can flood virally infected bacteria with toxic molecules, researchers discover

28.10.2024   |   Press monitoring

CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA with elegant precision. But it turns out that CRISPR systems have more than one strategy in their toolkit. A mechanism originally discovered in bacteria, where it has operated as an adaptive immune system for eons, CRISPR...

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AI-designed DNA switches flip genes on and off, allowing precise activation or repression

25.10.2024   |   Press monitoring

Researchers at The Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence to design thousands of new DNA switches that can precisely control the expression of a gene in different cell types. Their new approach opens the possibility of controlling when and where genes are...

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Unique mRNA delivery method could fix faulty genes before birth

23.10.2024   |   Press monitoring

A new study shows that a biomedical tool can successfully deliver genetic material to edit faulty genes in developing fetal brain cells. The technology, tested in mice, might have the potential to stop the progression of genetic-based neurodevelopmental conditions, such as Angelman syndrome and Rett syndrome, before birth. "The implications of...

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Team develops promising new form of antibiotic that makes bacterial cells self-destruct

21.10.2024   |   Press monitoring

To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system. Taking what they learned from a previous study on cancer, researchers from the University of Toronto (U of T) have developed novel compounds that trigger bacterial cells to self-destruct. The new form...

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Nano-nutrients can blunt effects of soil contamination, boost crop yields
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Nano-nutrients can blunt effects of soil contamination, boost crop yields

18.10.2024   |   Press monitoring

Research recently published in Nature Food by an international team of scientists led by the University of Massachusetts Amherst, Guangdong University of Technology, and Central South University of Forestry and Technology, has shown that nutrients on the nanometer scale can not only blunt some of the worst effects of heavy metal and metalloid...

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New bacteria-based therapy shows promise for fighting cancer
Credit: Gunnar Assmy - Fotolia.com

New bacteria-based therapy shows promise for fighting cancer

16.10.2024   |   Press monitoring

Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option. Owing to their ability to penetrate the rigid stromal barrier, bacteria can naturally target solid tumors and offer intratumoral penetration. However, before these bacteria can be used in medical...

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Gene-edited cells could halt multiple sclerosis progression

14.10.2024   |   Press monitoring

Our bodies have the ability to repair myelin, but in multiple sclerosis (MS), and as we age, this becomes less effective. There are currently no treatments to boost this process. Scientists have used gene-editing techniques to boost the repair of nerve cells damaged in multiple sclerosis, a study shows. The innovative method, which was tested in...

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Enzymes in spider venom have bioeconomic potential
Credit: Pink Badger - Fotolia.com

Enzymes in spider venom have bioeconomic potential

11.10.2024   |   Press monitoring

As venomous animals, spiders use their chemical arsenal for prey capture or defense. Small neurotoxins target the central nervous system of their victims. While the toxins are intensively investigated, scientists at the LOEWE Center for Translational Biodiversity Genomics (TBG) in Hesse, Germany, have turned their attention to the enzymes also...

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Nanobody capable of limiting the side effects of opioids discovered

9.10.2024   |   Press monitoring

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes to nearly half a million deaths worldwide each year. Researchers from the University of Geneva (UNIGE) have discovered a molecule, called nanobody...

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Phage cocktail shows promise against drug-resistant bacteria

7.10.2024   |   Press monitoring

Researchers have a new battle tactic to fight drug-resistant bacterial infections. Their strategy involves using collections of bacteriophages, viruses that naturally attack bacteria. In a new study, researchers at the University of Chicago Pritzker School of Molecular Engineering (PME) and UChicago Medicine have shown that a mixture of these...

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