Date: 21.12.2011
Overeating may cause brain aging while eating less turns on a molecule that helps the brain stay young.
A team of Italian researchers at the Catholic University of Sacred Heart in Rome have discovered that this molecule, called CREB1, is triggered by "caloric restriction" (low caloric diet) in the brain of mice. They found that CREB1 activates many genes linked to longevity and to the proper functioning of the brain.
The research appears this week in the Proceedings of the National Academy of Sciences (PNAS).
"Our hope is to find a way to activate CREB1, for example through new drugs, so to keep the brain young without the need of a strict diet," Dr Pani said.
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