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Research associate/ Staff scientist in signal pathways and molecular target profiling

Type of job: full-time

CZ-OPENSCREEN: National Infrastructure of Chemical Biology (Institute of Molecular Genetics, Prague) is seeking a highly-motivated candidate for cellular and biochemical profiling of bioactive compounds and potential drugs.

Job description:

  • Development and execution of HTS (high-throughput screening) experiments
  • Coordination of small team of 2-4 scientists/research associates
  • Tissue culture work using standard cancer cell lines and primary cells
  • Assay development for HTS profiling of compound libraries
  • Phenotype-based assays using widefield/confocal microscopy and label-free impedance-based technology
  • Advanced image analysis, data mining, cellular signaling pathways deconvolution, identification of new molecular targets and molecular mechanisms of bioactivity of bioactive compounds.

Required skills/qualification:

  • PhD in biochemistry and molecular/cell biology or related biomedical areas
  • Knowledge of cell signaling and biochemical pathways
  • Personal skills such as decision-making, ability to communicate and collaborate with other team members, effective time organization
  • Ability to present and publish the results of scientific work
  • Independence, creativity, flexibility, abstract and critical thinking
  • Excellent verbal and written communication skills in English

Salary and additional information:

We offer competitive salary dependent on candidate’s experience. The contract is initially for 1 year with the possible extension up to 5 years. Unique opportunity to work at state-of-the-art infrastructure in the multidisciplinary team of biochemists, biologists, medicinal chemists and cheminformaticians.

Social benefits:

5 weeks of vacations, sport facilities (squash, volleyball and basketball and fitness) are available at the campus.

Employment type: Full-time contract

Expected starting date: January 2018

How to apply: The job application should consist of Cover letter and structured CV to be sent to Mrs. Jana Brazinova ( jana.brazinova@img.cas.cz ) by 30 November, 2017.

For further information about our infrastructure and institute, please visit the following websites: www.openscreen.cz www.img.cas.cz

Mgr. Ing. Jana Bražinová



Updated: 7.11.2017


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